Cyprus became part of the Byzantine Empire after the partitioning of the Roman Empire in AD 395, and remained so for almost 800 years, though with brief period of Arab domination and influence.

After the rule of the rebellious Byzantine Emperor Isaac Comnenus, King Richard I of England captured the island in 1191 during the Third Crusade. On May 6, 1191, Richard's fleet arrived in the port of Lemesos and took the city. When Isaac arrived to stop the Crusaders he discovered he was too late and retired to Kolossi. Richard called Isaac to negotiations but Isaac broke his oath of hospitality and started demanding Richard's departure. Richard ordered his cavalry to follow him in a battle against Isaac's army in Tremetusia. The few Roman Catholics of the island joined Richard's army and so did the island's nobles who were dissatisfied with Isaac's seven years of tyrannical rule. Though Isaac and his men fought bravely, Richard's army was bigger and better equipped, assuring his victory. Isaac continued to resist from the castles of Pentadactylos but after the siege of his castle of Kantara he finally surrendered. In a fit of sardonic irony, Richard had Isaac confined with silver chains, scrupulously abiding by a previous promise that he would not place Isaac in irons should he be taken prisoner. Richard became the new ruler of Cyprus, gaining for the Crusade a major supply base that was not under immediate threat from the Turks as was Tyre. Richard looted the island and massacred those trying to resist him. He and most of his army left Cyprus for the Holy Land early in June. In his absence Cyprus would be governed by Richard Camville.

Guy of Lusignan purchased the island from Richard in 1192 compensated for the loss of his kingdom by purchasing Cyprus from the Templars. The Republic of Venice took control in 1489 after the death of the last Lusignan Queen, after which the Ottoman Empire conquered the Island in 1571.

Ottoman rule brought about two radical results in the history of the island. For the first time since the Phoenicians in the 9th century BC, a new population group appeared, the Turks. The Ottoman Empire gave timars--land grants--to soldiers under the condition that they and their families would stay there permanently. During the 17th century the Turkish population grew rapidly. Most of the Turks who had settled on the island during the three centuries of Ottoman rule remained when control of Cyprus--although not sovereignty--was ceded to Britain in 1878. Many, however, left for Turkey during the 1920s. By 1970, ethnic Turks represented 18% of the total population of the island, with ethnic Greeks representing the remainder. The distinction between the two groups was by religion and language.

The second important result of the Ottoman conquest benefited the Greek peasants who no longer remained serfs of the land they were cultivating. Now they could acquire it against payment, thus becoming owners of it. The Ottomans also applied the millet system to Cyprus, which allowed religious authorities to govern their own non-Muslim minorities. This system reinforced the position of the Orthodox Church and the cohesion of the ethnic Greek population. Gradually the Archbishop of Cyprus became not only religious but ethnic leader as well. In this way the Church undertook the task of the guardian of Greek cultural legacy which is partly carried on even now, although diminished after independence.

The heavy taxes and the abuses against the population on the part of the Ottoman rulers in the early years after the Ottoman conquest gave rise to opposition, following which the Sultan ordered the Governor (the "Kadi") and the Treasurer to govern with justice. While the Sultan's orders indicated his goodwill towards the local population, the local administration proved indifferent, arbitrary and often corrupt, along with imposing a heavy burden of taxes.[citation needed] The inhabitants of Cyprus, disappointed at the mismanagement of Ottoman governors, soon turned to Western Europe in search for help for liberation.

Between 1572 and 1668 AD about 28 bloody uprisings took place on the island and in many of these both Greeks and Turk peasants took part. But all of them ended in failure.

About 1660 AD, in order to eliminate the mismanagement of the Ottoman administration, the Sultan recognised the Archbishop and the Bishops as "the protectors of people" and the representatives of the Sultan. In 1670 AD, Cyprus ceased to be a "pasaliki" for the Ottoman Empire and came under the jurisdiction of the Admiral of the Ottoman fleet. In his turn, the Admiral sent an officer to govern in his place.

In 1703 AD Cyprus came under the jurisdiction of the Grand Vizier (Anthony Petane) who sent to the island a military and civil administrator. The title and function of this officer were awarded to the person who could raise the highest revenues in exchange. As a result, even heavier taxation was imposed. About 1760 AD the situation in Cyprus was intolerable. A terrible epidemic of plague, bad crops and earthquakes, drove many Cypriots to emigrate. In addition, what was worse for the Greeks and Turks of the island, the newly- appointed Pasha, doubled the taxes in 1764 AD. In the end Chil Osman and 18 of his friends were killed by Greek and Turkish Cypriots alike but the two ethnic elements had to pay a huge sum of money to the Sultan and the families of the victims. The latter did not accept this judgement and broke into an open rebellion, having Khalil Agha, the commander of the guard of the castle of Kyrenia, as their leader. Finally the uprising was crushed and Khalil Agha was beheaded.

Cyprus was placed under British control on 4 June 1878 as a result of the Cyprus Convention, which granted control of the island to Britain in return for British support of the Ottoman Empire in the Russian-Turkish War.

Famagusta harbour was completed in June 1906; by this time the island was a strategic naval outpost for the British Empire, shoring up influence over the Eastern Mediterranean and Suez Canal, the crucial main route to India.

Cyprus was formally annexed by the United Kingdom in 1913 in the run-up to the First World War. Many Cypriots, now British subjects, signed up to fight in the British Army, in this and in the Second World War.

During the 1900s and 1950s, Cypriots began to demand union with Greece. In 1950, over 95% of the population (including both Greek and Turkish Cypriots)[citation needed] voted in a referendum in support of annexation, while the British sought to quell any movement which could threaten their possession of the island. In 1955 the struggle against British rule erupted with the foundation of EOKA, which lasted until 1959.

Independence was attained in 1960 after exhaustive negotiations between the United Kingdom, as the colonial power, and Greece and Turkey, the cultural 'motherlands' for both of the communities in Cyprus. The UK ceded the island under a constitution allocating government posts and public offices by ethnic quota, but retained two small Sovereign Base Areas.The constitution, that was signed by both sides was later reneiged on by the first Greek Cypriot President leader Archbishop Makarios III, his Vice President was the leading Turkish Cypriot politician Dr Fazıl Küçük.